Reduction of highest priority critically important (HPCIA) antibiotic use

In 2025, the team at Animal Trust Dewsbury were recognised for reducing their use of highest-priority, critically important antibiotics (HPCIAs) whilst ensuring that any use followed the principles of good antimicrobial stewardship. Changes were incrementally introduced, and by the end of the project, the prescription rates for HPCIAs fell from 3% to just 0.46% of all consultations.

Key takeaways

• Culture and sensitivity testing became central: The practice prioritised culture and sensitivity (C&S) testing before prescribing HPCIAs, helping ensure antibiotics were used only when necessary and appropriate.
• Stock control and alternative medications supported stewardship: By restricting the availability of HPCIAs from stock and increasing the availability of first-line alternatives, the team created barriers to inappropriate prescribing and made responsible choices easier.
• Team training and engagement were key to success: Regular clinical meetings, nurse-led stock control, and open discussion fostered strong team buy-in, helping overcome barriers to change and embed antimicrobial stewardship into daily practice

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